Dextrose Monohydrate is used as a sweetener, a fermentation substrate, an humectant or a carrier in a large scope of applications such as confectionery, bakery, snacks, beverages and dairy products.

Dextrose monohydrate in pharmaceutical industry is used in powder and tablet form and in isotonic and hypertonic solutions for medical purposes. It is combined with vitamin D and minerals such as calcium are used for the preparation of glucose tablets. It is also used to treat diabetic patients' hypoglycaemia. In combination with ascorbic acid it can be used to treat various disorders, heart problems and concerns pertaining  to intoxications.

Dextrose monohydrate finds increasing use in confectioneries. It is commonly used in the manufacturing of diverse confectionery items such as chewing gums and chocolates. It also has great preservative properties, which increases the end product's shelf life. This has contributed to increased use of dextrose monohydrate in confectionaries.